Current Treatment Options for Cognitive Impairment in Bipolar Disorder: a Review

Abstract

Cognitive impairment is a key feature of bipolar disorder (BD) which often persists into euthymia. This impairment appears to be independent, to an extent, of mood symptoms and is associated with deficits in overall functioning. Priority should thus be given to research investigating adjunctive treatments aimed at improving cognitive functioning in BD. This paper systematically reviews studies specifically examining changes in cognitive functioning in relation to pharmacological and/or psychosocial interventions in adults with BD. Eighteen studies were included in the review: 11 examining pharmacological interventions and seven examining psychosocial interventions. Findings from the reviewed..